Twist and torque in the cellular nanocosmos: Diez group detects biophysical forces of molecular motors in 3D
Publication: Dynamic Guiding of Motor-Driven Microtubules on Electrically Heated, Smart Polymer Tracks
Nano Lett., in press (2013)
Biomolecular motor systems are attractive for future nanotechnological devices because they can replace nanofluidics by directed transport. However, the lack of methods to externally control motor-driven transport along complex paths limits their range of applications. Based on a thermo-responsive polymer, we developed a novel technique to guide microtubules propelled by kinesin-1 motors on a planar surface. Using electrically heated gold microstructures, the polymers were locally collapsed, creating dynamically switchable tracks that successfully guided microtubule movement.
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V. Schroeder, T. Korten, H. Linke, S. Diez: Dynamic Guiding of Motor-Driven Microtubules on Electrically Heated, Smart Polymer Tracks, Nano Letters, in press (publication date web: June 10, 2013).
doi: 10.1021/nl402004sBack to News Ticker