Twist and torque in the cellular nanocosmos: Diez group detects biophysical forces of molecular motors in 3D
VW-Stiftung is funding research on "Microscope-free operation of macroscopic devices based on molecular motors"
Prof. Stefan Diez, group leader at B CUBE, and his colleague Prof. Heiner Linke (Lund University, Sweden) are starting a collaborative research project on the "Microscope-free operation of macroscopic devices based on molecular motors". The project will be funded by the VW Stiftung for three years with a total sum of about 740.000 Euro.
The project aims to design and test strategies to detect and quantify the activity of biomolecular transport systems in a manner that is microscope-free and allows for direct interfacing with digital electronics. In particular, the kinesin-microtubule transport system will be probed with highly-localized, nanoscopic check points and read out the presence of filaments as (opto-)electrical signals. As a result, significant advances in the development and testing of novel sensor systems are expected, as well as in a new class of miniaturized, microscope-free protein detection systems relevant for large-scale and high-throughput biocomputation and point-of-care molecular-diagnostics applications. Link: http://portal.volkswagenstiftung.de/search/projectDetails.do?ref=93439
This project is funded within the initiative "Integration Molecular Component in Functional Macroscopic Systems” by the VolkswagenStiftung. This initiative is focused on projects in the sciences, engineering and medicine linking up molecular or nanoscale units to form complex functional systems. Link: https://www.volkswagenstiftung.de/en/funding/completed-initiatives/macroscopic-functional-systems.html