We develop novel optical techniques to investigate molecular transport processes in cell biology and nanotechnology. Focus: Single-molecule imaging with 3D nm-precision.
We study various kinesin motors during transport along microtubules and depolymerisation of microtubules. Focus: Protofilament switching and motor behaviour at obstacles.
We reconstitute subcellular mechano-systems to study cooperative effects in motor activity. Focus: Bidirectional transport, membrane-anchored motors and filament crosslinking.
We apply biomolecular motors in engineered environments towards the generation, manipulation and detection of nano structures. Focus: External motility control and molecular diagnostics.