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Zhang Group - Selection vs. Screening

Nature develop specific binding molecules (e.g. antibody) using selection, while human discover small molecule drugs using screening. The emerging field of DNA encoded chemical library allows us to perform selection of small molecule compounds. We combine both technologies, to illustrate their advantages and disadvantages, and to discover high specific inhibitors against proteins of medicinal interest.

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- Rational Drug Design

- Cell Culture in 3D

- Isomerization